Research Article
Advanced UPLC-MS/MS Method for the Quantification of SIPI6398 in Rat Plasma and Its Pharmacokinetic Characterization
Table 1
Accuracy, precision, matrix effect, and recovery of SIPI6398 in rat plasma.
| | Concentration (ng/mL) | Accuracy (%) | Precision (%RSD) | Matrix effect (%) | Recovery (%) | | Intra-day | Inter-day | Intra-day | Inter-day |
| | 4 | 96.2 | 104.0 | 10.8 | 8.2 | 89.4 | 80.7 | | 160 | 99.0 | 90.5 | 4.3 | 9.6 | 92.2 | 80.9 | | 1600 | 104.7 | 105.5 | 1.0 | 5.1 | 92.6 | 83.3 |
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