Research Article
A Causal Relationship Between Type 1 Diabetes and Risk of Osteoporosis: A Univariable and Multivariable Mendelian Randomization Study
Table 1
Two-sample Mendelian randomization analysis of the association of type 1 diabetes with the risk of osteoporosis.
| | Exposure-outcome | No. of SNP | Methods | OR (95% CI) | value |
| | T1D-osteoporosis | 28 | MR-Egger | 1.08 (1.03 to 1.15) | 0.006 | | | Weighted median | 1.08 (1.03 to 1.13) | < 0.001 | | | Inverse variance weighted | 1.06 (1.02 to 1.10) | 0.002 | | | Simple mode | 1.07 (0.97 to 1.19) | 0.201 | | | Weighted mode | 1.08 (1.03 to 1.12) | 0.002 |
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